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Home > West Medicine > Internal Medicine > Neurology
G93.700

Reye Syndrome

神经内科

Common symptoms

肝功能异常、出血倾向、咽痛、嗜睡、腹泻、衣玉品、呼吸异常、意识障碍、烦躁不安、颅内压增高、神志恍惚

The pathology of disease

Reye syndrome is an acute, life-threatening encephalopathy with fatty liver degeneration, occurring in children after a viral illness (influenza/chickenpox), associated with aspirin use. Clinical: persistent vomiting, lethargy/confusion, seizures, and coma, with raised transaminases and hyperammonemia. Treatment: supportive ICU care, control ICP and ammonia, correct metabolic derangements; it is largely prevented by avoiding aspirin in children with viral illness.

Common Symptoms

Persistent vomiting after viral illness; lethargy/confusion; seizures; coma; raised transaminases/ammonia

Causes and Pathogenesis

Aspirin during viral illness causes mitochondrial injury with hepatic fatty change and cerebral edema.

Treatment

Supportive ICU; control ICP/ammonia; correct metabolic derangements; avoid aspirin

Preventive Measures

Avoid aspirin in children with viral illness; prompt treatment.

Department to Visit

It is recommended to visit the Pediatrics department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.