Interstitial nephritis

Interstitial nephritis, also called tubulointerstitial nephritis, is a clinical-pathologic syndrome of acute or chronic tubulointerstitial damage from various causes, clinically divided into acute and chronic interstitial nephritis. Acute interstitial nephritis causes short-time inflammatory cell infiltration, interstitial edema and varying tubular damage with renal insufficiency; most cases have a clear cause, and removing it allows recovery. Chronic interstitial nephritis is characterized by renal interstitial fibrosis, mononuclear infiltration and tubular atrophy.

Common Symptoms

Immune nephritis; weakness; facial butterfly rash; tubulointerstitial nephritis; hematuria; nocturia; nausea; polyuria

Causes

Causes of acute interstitial nephritis: ① drugs: antibiotics, NSAIDs, analgesics, anticonvulsants, diuretics, proton-pump inhibitors; ② infection: bacteria, viruses, parasites, mycoplasma, chlamydia; ③ autoimmune diseases. Chronic forms involve long-term drug toxicity, infection, autoimmune disease and metabolic causes.

Treatment

Medication, supportive treatment

Prevention

Remove the cause, avoid nephrotoxic drugs, treat infection promptly, and monitor renal function.

Recommended Department

It is recommended to visit the nephrology department; before the visit you may first book an appointment and connect with experts through this platform.

Warm reminder: The above information is provided for health education reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek care at a regular hospital in time.