Renal damage in leukemia

Leukemia is a malignant leukocyte proliferation; when cells enter the blood they infiltrate and destroy other tissues and organs. Leukemia can cause renal damage; the kidney is the 3rd most commonly infiltrated organ in acute leukemia, mainly by direct infiltration or metabolites, also via immune reactions and electrolyte disturbance, presenting as acute renal failure, chronic renal insufficiency, nephritic or nephrotic syndrome.

Common Symptoms

Proteinuria; chronic renal insufficiency; anuria; urinary calculus; polyuria; diabetes insipidus

Causes

Renal damage may relate to the kidney being hematopoietic in embryogenesis; acute leukemia most often infiltrates the kidney, especially acute monocytic and lymphoblastic leukemia; leukemic cells directly infiltrate the renal parenchyma.

Treatment

Treat leukemia, supportive renal care

Prevention

Monitor renal function during leukemia treatment.

Recommended Department

It is recommended to visit the hematology department; before the visit you may first book an appointment and connect with experts through this platform.

Warm reminder: The above information is provided for health education reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek care at a regular hospital in time.