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Home > West Medicine > Internal Medicine > Hematology
百科

Myelodysplastic syndrome

血液科

Common symptoms

颅内出血、淋巴结肿大、肝脾肿大、驻站医、官爵银、面色苍白、鼻衄、牙龈出血、乏力、鼻出血

The pathology of disease

Myelodysplastic syndrome (MDS) is a heterogeneous clonal disorder of hematopoietic stem/progenitor cells with dysplasia, ineffective hematopoiesis, and high risk of transformation to AML. Incidence 10-12/100,000; >50 years in 50-70%; M:F = 2:1.

Common Symptoms

Intracranial hemorrhage; lymphadenopathy; hepatosplenomegaly; pallor; epistaxis; gingival bleeding; fatigue

Causes

Stem/progenitor cell clonal disorder; retroviruses, oncogene mutations, tumor suppressor loss. Benzene, alkylating chemo, radiation; age-related DNA repair decline.

Treatment

Drug therapy; supportive care

Prevention

Avoid benzene/radiation/alkylating agents.

Recommended Department

It is recommended to visit the hematology department; before the visit you may first book an appointment and connect with experts through this platform.

Warm reminder: The above information is provided for health education reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek care at a regular hospital in time.