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淋巴结肿大、疲乏、血小板减少、低热、肝脏肿大
Hairy-cell leukemia is a rare chronic clonal B-cell proliferative disorder; pathologic B cells have hair-like cytoplasmic projections (hairy cells, HC). HC mainly infiltrate marrow and spleen; clinically splenomegaly, cytopenias, and numerous HC in peripheral blood/marrow.
Lymph-node enlargement; fatigue; thrombocytopenia; low fever; hepatomegaly
Unknown; HTLV-II/EBV/radiation/organic solvents debated; familial cases + chr12/14q/5/del(5q13) abnormalities suggest genetic factors.
Drug, supportive, surgery
Avoid excessive X-rays/radiation; PPE for radiation workers; pregnant women/infants avoid radiation. Don't abuse chloramphenicol/cytotoxic/immunosuppressants.
It is recommended to visit the Hematology department; an appointment can be booked on this platform before the visit.
Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.
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