医
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淋巴结肿大、刷牙出血、巨脾症、心悸伴乏力、面色苍白、面色苍白、黏膜出现出血点、乏力、低热
Chronic myelomonocytic leukemia (CMML) is a chronic myeloid leukemia. Incidence ~1-2/100,000/y; age >60; M:F 1.5-3:1. Two symptom groups: myelodysplastic and myeloproliferative. Myelodysplastic cytopenias: fatigue, palpitations, pallor, low fever, infection/bleeding. Myeloproliferative: abnormal monocytosis with infiltration (skin/glands/gingiva/bone), nodes/hepatosplenomegaly, even massive splenomegaly. In 24 reported cases: 50% hepatomegaly, 45.8% splenomegaly, 20.8% nodal involvement.
Lymph-node enlargement; gingival bleeding on brushing; massive splenomegaly; palpitations with fatigue; pallor; mucosal petechiae; fatigue; low fever
Pluripotent hematopoietic-stem-cell origin; erythroid dysfunction, platelet abnormalities, lymphocyte dysfunction. Mainly granulomonocytic lineage; in-vitro culture = CFU-GM. Chromosomes usually normal.
Drug, supportive therapy
(1) Avoid harmful factors (chemicals/ionizing radiation) in pregnant women/children; PPE; avoid indoor pollution; rational drug use. (2) Prevent infections (especially viral); vaccination.
It is recommended to visit the Hematology department; an appointment can be booked on this platform before the visit.
Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.
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