ChineseChina UKUK DeutschlandDeutschland FranceFrance РоссияРоссия 한국한국 ไทยไทย Việt NamViệt Nam العربيةالعربية ҚазақстанҚазақстан EspañaEspaña MyanmarMyanmar DaiDai

Linking China’s Premium Healthcare · Serving Global Health Needs

Breaking down language, channel and process barriers in cross-border care — making the best doctors your personal doctors.
300 Grade-A partner hospitals · 3,000+ leading experts · one-stop service across all specialties

One-Stop Medical Care in China

  • International flights · Airport pickup · Nearby hotels
  • Multilingual interpreters · Full medical escort
  • Expert matching · Hospital fast-track
  • Full-cycle treatment · Post-op follow-up
Sign in
Home > West Medicine > Internal Medicine > Hematology
C94.700x004

CNS Leukemia (CNS-L)

血液科

Common symptoms

颈强直、颅内出血、三叉神经一二支...、面神经瘫痪、凝血障碍、血小板减少、抽搐、神志不清、颅内压增高、脊髓出血

The pathology of disease

CNS leukemia (CNS-L) refers to clinical signs/symptoms from extramedullary leukemic-cell infiltration of the leptomeninges or adjacent neural tissue; a common leukemia complication with major prognostic impact. Causes corresponding neurologic/psychiatric symptoms. Leukoencephalopathy can occur at any stage.

Common Symptoms

Neck stiffness; intracranial hemorrhage; trigeminal V1/V2; facial palsy; coagulopathy; thrombocytopenia; convulsions; altered consciousness; raised ICP; spinal-cord hemorrhage

Causes and Pathogenesis

Chemical leukemogens: benzene/nitrosamines/phenylbutazone/chloramphenicol; cytotoxic chemo (nitrogen mustard/cyclophosphamide/procarbazine/VP16/VM26). Ionizing radiation (dose-dependent; Co-60 exposure). RNA retroviruses (T-cell type). Chromosomal aberrations.

Treatment

Drug, supportive therapy

Preventive Measures

(1) Patient education; bed rest; minimize visitors. (2) Clean disinfected ward; no smoking; light diet; regular bowel. (3) Monitor mental status/vitals/temperature/pulse/respiration/BP.

Department to Visit

It is recommended to visit the Hematology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.