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恶性贫血、流产、食欲减退、血小板减少、乏力、手足麻木、感觉障碍
Folate deficiency causes megaloblastic anemia, glossitis, diarrhea, and elevated homocysteine; in pregnancy it increases fetal neural-tube-defect risk. Causes: poor fresh-vegetable intake, alcoholism, malabsorption, pregnancy, hemodialysis, and drugs (methotrexate, anticonvulsants). Treatment: oral folic-acid supplementation; routine periconceptional folate prevents neural-tube defects.
Fatigue; pallor; glossitis; diarrhea; megaloblastic anemia; pregnancy neural-tube-defect risk
Dietary folate insufficiency/demand increase impairs DNA synthesis, causing megaloblastic erythropoiesis and epithelial turnover defects.
Oral folic acid; periconceptional supplementation; treat underlying cause; ensure B12 co-deficiency is also corrected
Folic-acid-fortified foods; periconceptional folate; green-leafy vegetables; avoid excess alcohol.
It is recommended to visit the Hematology department; an appointment can be booked on this platform before the visit.
Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.
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