Takayasu Disease (Multiple Great-vessel Arteritis)

Takayasu disease is a chronic granulomatous vasculitis of the aorta and its branches, causing segmental stenosis/occlusion/aneurysm, predominantly in young women. Clinical: pulselessness, BP difference, arm claudication, visual disturbance, and systemic symptoms. Treatment: glucocorticoids and steroid-sparing immunosuppressants; control risk factors; surgical/endovascular revascularization for cerebral/limb/renal ischemia after disease quiescence; long-term vascular imaging follow-up.

Common Symptoms

Pulselessness; BP discrepancy; claudication; visual disturbance; young women

Causes and Pathogenesis

Granulomatous inflammation of large-vessel media causes wall thickening, stenosis, and aneurysmal dilatation.

Treatment

Glucocorticoids/immunosuppressants; control risk factors; revascularization after quiescence

Preventive Measures

Early diagnosis; treat active inflammation; long-term vascular imaging.

Department to Visit

It is recommended to visit the Rheumatology/Vascular-surgery department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.