Discoid Lupus Erythematosus

Discoid lupus erythematosus (DLE) is chronic scarring photosensitive erythematous plaques with follicular plugging/atrophy/telangiectasia on face/scalp/ears, 5-10% progress to systemic SLE. Treatment: strict sun protection (SPF 50+, hats); topical/intralesional corticosteroids; topical calcineurin inhibitors (tacrolimus/pimecrolimus); oral hydroxychloroquine; oral retinoids (acitretin); dapsone; methotrexate/azathioprine for refractory; evaluate ANA/C3/C4/dsDNA/urinalysis for systemic involvement; monitor scarring alopecia; follow-up dermatology/rheumatology.

Common Symptoms

Chronic scarring erythematous plaques; follicular plugging; face/scalp/ears; photosensitive

Causes and Pathogenesis

Autoimmune B/T-cell dysregulation + UV damage causes interface dermatitis and scarring.

Treatment

Sun protection; topical/intralesional steroids; calcineurin; hydroxychloroquine; monitor SLE

Preventive Measures

Sun protection; avoid smoking; evaluate systemic disease.

Department to Visit

It is recommended to visit the Dermatology/Rheumatology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.