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Home > West Medicine > Internal Medicine > Rheumatology
D86.900

Sarcoidosis

风湿免疫科

Common symptoms

肝脾肿大、冻疮、呼吸困难、盗汗、乏力、肝肿大、角膜炎、碱性磷酸酶增高、颈部淋巴结肿大

The pathology of disease

Sarcoidosis is a multisystem noncaseating granulomatous disease of unknown cause, commonly affecting the lungs and hilar lymph nodes, skin, eyes and liver. It occurs in young/middle-aged adults; features include bilateral hilar lymphadenopathy, erythema nodosum, cough, dyspnea, uveitis, hypercalcemia. Most cases self-resolve; some progress to pulmonary fibrosis.

Common Symptoms

Cough; dyspnea; bilateral hilar lymphadenopathy; erythema nodosum; uveitis; fever; fatigue; hypercalcemia

Causes and Pathogenesis

Unknown antigen triggers CD4 T-cell-driven noncaseating granulomatous inflammation in affected organs; genetic/environmental factors.

Treatment

Observation; oral corticosteroids for symptomatic/organ-threatening disease; steroid-sparing agents

Preventive Measures

Regular follow-up; monitor pulmonary/ocular/cardiac/neural involvement; avoid tobacco.

Department to Visit

It is recommended to visit the Respiratory department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.

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