Hemorrhagic cystitis

Hemorrhagic cystitis is acute or chronic bladder injury from certain drugs or chemicals in urine, causing diffuse inflammatory bleeding. It is a multifactorial complication common during cancer treatment, mostly from anticancer drug toxicity or allergy, or radiation injury from high-dose pelvic irradiation; also seen with some viral infections such as adenovirus and influenza.

Common Symptoms

Hematuria; sacral hypoplasia

Causes

Many substances cause bladder bleeding: alkylating agents, busulfan, thiotepa, aniline, toluidine derivatives, insecticides, and some viruses such as adenovirus and influenza. The bladder is the last organ storing/excreting these drugs in concentrated urine, chronically irritating the mucosa.

Treatment

Stop the offending agent, bladder irrigation, supportive care

Prevention

Hydration during cytotoxic therapy and monitor for hematuria.

Recommended Department

It is recommended to visit the urology department; before the visit you may first book an appointment and connect with experts through this platform.

Warm reminder: The above information is provided for health education reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek care at a regular hospital in time.