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癫痫和癫痫样发作、瘫痪、结节、意识障碍、抽搐、定位体征、颅内压增高、腱反射亢进
Cerebral schistosomiasis: egg granulomas in brain, 2-4% of schistosomiasis; usually from lung lesions. Temporo-occipital cortical/subcortical abscesses/eosinophilic granulomas; acute (meningoencephalitis) vs chronic (seizures/intracranial hypertension).
Seizure; paralysis; nodule; altered consciousness; convulsion; focal signs; ICP elevation; hyperreflexia
Life cycle: adult/egg/miracidium/sporocyst/cercaria/schistosomulum. S. japonicum 1000-3000 eggs/day (10× mansoni/haematobium). Egg granuloma = cell-mediated delayed hypersensitivity (SEA → T cells; Th1 IL-2/IFN-γ; Th2 IL-4/5/10; TNF-2/IL-1). Japanese = clustered eggs, abscess-like liquefaction, PMN/PL-rich granulomas. Acute = mixed immune; chronic = delayed. Brain: frontoparietal/temporal gray-white junction; gliosis/edema; adults not found in cerebral veins.
Drug therapy, supportive therapy
Screen/treat patients/livestock; fecal management; snail control; avoid infested water.
It is recommended to visit the Neurosurgery department; an appointment can be booked on this platform before the visit.
Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.
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