Olfactory-Groove Meningioma

Olfactory-groove meningioma attaches to anterior-fossa floor cribriform plate/posterior; unilateral/bilateral (unilateral common); may extend contralaterally.

Common Symptoms

Tremor; visual impairment; hemianopia; hallucination; olfactory disturbance; raised ICP; unilateral optic-nerve atrophy; anosmia; bradyphrenia

Causes and Pathogenesis

(1) Etiology: unknown; environment + gene mutation; trauma/radiation/virus/bilateral acoustic neuroma. Accelerated arachnoid-cell division. 4 classes: meningothelial, mesenchymal non-meningothelial, primary melanocytic, uncertain origin. (2) Mechanism: meningothelial; from arachnoid villi/embryonic remnants. 11 subtypes: meningothelial (53.5%), fibrous, transitional, psammomatous, vascular, microcystic, secretory, clear-cell, chordoid, lymphoplasmacyte-rich, metaplastic. Spherical (common) vs flat (≤1cm, skull base). Rich vascular supply (ECA/ICA/vertebrobasilar dual). Dark-red cut; lipid-laden cream-yellow areas; woven pattern; calcified psammoma bodies; occasional cysts. WHO grade I.

Treatment

Surgery, rehabilitation

Preventive Measures

1988 US report: ~80% cancers preventable by lifestyle; 1969 Higginson: 90% environmental. Air/water/food/habits/social relations.

Department to Visit

It is recommended to visit the Neurosurgery department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.