Autoimmune Hepatitis

Autoimmune hepatitis is immune-mediated chronic hepatitis (type 1/2), presenting with fatigue, jaundice, elevated transaminases/IgG, and autoantibodies (ANA/SMA/LKM), progressing to cirrhosis. Treatment: induction (prednisone/prednisolone ± azathioprine); maintenance (azathioprine/6-mercaptopurine); monitor remission (enzymes/IgG/biopsy); treat flares; avoid abrupt withdrawal; screen for hepatocellular carcinoma if cirrhosis; liver transplant evaluation for refractory/decompensated; treat associated autoimmune diseases; follow-up.

Common Symptoms

Fatigue; jaundice; elevated transaminases/IgG; autoantibodies

Causes and Pathogenesis

Immune dysregulation causes hepatocyte inflammation and fibrosis.

Treatment

Corticosteroids + azathioprine; monitor remission; screen HCC; transplant eval

Preventive Measures

Early diagnosis; regular monitoring; avoid hepatotoxins.

Department to Visit

It is recommended to visit the Gastroenterology/Hepatology/Rheumatology/Transplant department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.