Hypertrophic Obstructive Cardiomyopathy

Hypertrophic obstructive cardiomyopathy is asymmetric septal hypertrophy causing left-ventricular outflow tract obstruction, presenting with dyspnea, angina, syncope, and sudden cardiac death risk. It is genetic (sarcomere mutation). Treatment: beta-blocker/non-dihydropyridine CCB; avoid vasodilators/diuretics; septal reduction therapy (myectomy/alcohol septal ablation) for symptomatic obstruction; ICD for sudden-death prevention; family screening.

Common Symptoms

Dyspnea/angina; exertional syncope; systolic murmur; asymmetric septal hypertrophy; family history

Causes and Pathogenesis

Sarcomere gene mutation causes myocardial hypertrophy and LV outflow obstruction.

Treatment

Beta-blocker/verapamil; septal reduction (myectomy/ablation); ICD for SCD risk; family screening

Preventive Measures

Avoid intense competitive sport; family screening; ICD for high risk.

Department to Visit

It is recommended to visit the Cardiology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.