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Home > West Medicine > ENT & Ophthalmology > ENT

Classroom classification

百科

Aspirin intolerance triad

耳鼻喉科

Common symptoms

胸闷、休克、变应性鼻炎

The pathology of disease

Aspirin intolerance triad (Samter triad / AERD) is asthma + aspirin/NSAID sensitivity + nasal polyps; chronic rhinosinusitis; adult onset; exacerbated by COX-1 inhibitors.

Symptoms

Asthma; nasal polyps; aspirin/NSAID triggers bronchospasm/rhinitis; after aspirin; adult

Causes

COX-1 inhibition; leukotriene overproduction; chronic eosinophilic airway disease.

Treatment

Avoid aspirin/NSAIDs; leukotriene antagonists; topical nasal steroids; aspirin desensitization

Dept

Allergy / pulmonology / ENT.

Warm reminder: Health education reference only; seek care at regular hospital.

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