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Home > West Medicine > Pediatrics > Pediatric Internal Med
百科

Leukocyte adhesion deficiency type I

小儿内科

Common symptoms

软组织感染、真菌感染、反复感染、脐带感染

The pathology of disease

Leukocyte adhesion deficiency type I is CD18 defect; no pus formation; recurrent bacterial infections; leukocytosis; delayed umbilical cord separation; childhood; bone marrow transplant.

Symptoms

Recurrent bacterial infections; no pus; leukocytosis; delayed umbilical cord separation; periodontitis; child; poor wound healing

Causes

ITGB2 (CD18) mutation; autosomal recessive; leukocyte adhesion defect.

Treatment

Prophylactic antibiotics; bone marrow transplant; aggressive infection control; immunology; genetics

Dept

Immunology / pediatrics / infectious disease.

Warm reminder: Health education reference only; seek care at regular hospital.