Prurigo Nodularis

Prurigo nodularis is chronic pruritic hypertrophic nodules (lichenified from repeated scratching), on extensor surfaces/back, often linked to atopic dermatitis/systemic disease (renal/hepatic/thyroid/hematologic). Treatment: identify/treat underlying cause; topical corticosteroids/intralesional steroids; emollients; antihistamines; gabapentin/pregabalin; phototherapy (NB-UVB/PUVA); dupilumab/apremilast for refractory; treat atopic dermatitis; prevent scratching (nail trimming/occlusion); follow-up dermatology.

Common Symptoms

Pruritic hypertrophic nodules; extensor surfaces/back; chronic scratching

Causes and Pathogenesis

Chronic pruritus-scratch cycle causes nodular lichenification.

Treatment

Topical/systemic steroids; antihistamines; gabapentinoids; dupilumab; phototherapy

Preventive Measures

Control pruritus; avoid scratching; treat underlying disease.

Department to Visit

It is recommended to visit the Dermatology/Allergy department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.