ChineseChina UKUK DeutschlandDeutschland FranceFrance РоссияРоссия 한국한국 ไทยไทย Việt NamViệt Nam العربيةالعربية ҚазақстанҚазақстан EspañaEspaña MyanmarMyanmar DaiDai

Linking China’s Premium Healthcare · Serving Global Health Needs

Breaking down language, channel and process barriers in cross-border care — making the best doctors your personal doctors.
300 Grade-A partner hospitals · 3,000+ leading experts · one-stop service across all specialties

One-Stop Medical Care in China

  • International flights · Airport pickup · Nearby hotels
  • Multilingual interpreters · Full medical escort
  • Expert matching · Hospital fast-track
  • Full-cycle treatment · Post-op follow-up
Sign in
Home > West Medicine > Other Specialties > Dermatology
L40.300

Palmoplantar Pustulosis

皮肤科

Common symptoms

鳞屑、脓疱、瘙痒、丛伊可

The pathology of disease

Palmoplantar pustulosis is chronic recurrent pustular eruption on palms/soles (sterile yellow-brown pustules on erythematous base), associated with smoking, HLA-B27, and SAPHO syndrome. Treatment: topical corticosteroids; coal tar; topical calcipotriol; phototherapy (NB-UVB/PUVA); systemic acitretin/methotrexate/cyclosporine; avoid smoking (strong association); anti-TNF/IL-17/IL-23 biologics for severe; treat associated SAPHO/jaw osteitis; follow-up dermatology/rheumatology.

Common Symptoms

Sterile palmoplantar pustules; erythema; chronic; smoking-associated

Causes and Pathogenesis

Autoimmune reaction (smoking/HLA) causes sterile pustular inflammation.

Treatment

Topical steroids; coal tar; phototherapy; acitretin; biologics; stop smoking

Preventive Measures

Stop smoking; early treatment; monitor associated disease.

Department to Visit

It is recommended to visit the Dermatology/Rheumatology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.