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Home > West Medicine > Other Specialties > Dermatology
L40.501†

Psoriatic Arthritis

皮肤科

Common symptoms

丘疹、脓疱、瘙痒、剥脱性皮炎

The pathology of disease

Psoriatic arthritis is seronegative spondyloarthropathy associated with psoriasis, presenting with peripheral oligo/polyarthritis, dactylitis, enthesitis, spinal involvement, and nail changes. Treatment: NSAIDs; methotrexate/leflunomide/sulfasalazine for peripheral disease; TNF inhibitors (etanercept/adalimumab/infliximab); IL-17 inhibitors (secukinumab/ixekizumab/brodalumab); IL-23 inhibitors (guselkumab/risankizumab); apremilast; JAK inhibitors upadacitinib; topical skin therapy (corticosteroids/vitamin-D analogs/phototherapy); physical therapy; monitor joint damage (X-ray/MRI); cardiovascular/metabolic screening; follow-up rheumatology/dermatology.

Common Symptoms

Peripheral arthritis; dactylitis; enthesitis; nail psoriasis; skin plaques

Causes and Pathogenesis

Immune dysregulation (IL-17/IL-23/TNF) causes joint and skin inflammation.

Treatment

NSAIDs; DMARDs; biologics (TNF/IL-17/IL-23); topical skin therapy; PT

Preventive Measures

Early treatment; cardiovascular risk control; physical activity.

Department to Visit

It is recommended to visit the Rheumatology/Dermatology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.