Erythema Multiforme Exudativum

Erythema multiforme exudativum is hypersensitivity eruption with target lesions (acral, symmetric), minor (HSV-associated) or major (mucosal involvement, Mycoplasma/drug). Treatment: identify/treat cause (HSV: acyclovir prophylaxis; Mycoplasma: macrolide; stop culprit drug); supportive care; topical corticosteroids; oral care; systemic corticosteroids for severe major (controversial); monitor for SJS/TEN overlap; eye/ENT/urology care if mucosal; follow-up dermatology/infectious disease.

Common Symptoms

Target lesions; acral symmetric; mucosal involvement; by HSV/Mycoplasma/drug

Causes and Pathogenesis

Hypersensitivity reaction causes keratinocyte apoptosis and target lesions.

Treatment

Treat cause; supportive care; topical/systemic steroids; monitor SJS/TEN

Preventive Measures

Avoid culprit drugs; HSV prophylaxis; treat Mycoplasma.

Department to Visit

It is recommended to visit the Dermatology/Infectious-disease/Emergency department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.