Erythema Elevatum Diutinum

Erythema elevatum diutinum (EED) is chronic red-brown/yellow papules/plaques on extensor extremities (knuckles/elbows/knees/ankles), associated with HIV/hepatitis/bacterial infection/IgA monoclonal gammopathy. Treatment: dapsone (first-line); topical/intralesional corticosteroids; oral retinoids; cyclophosphamide; investigate/treat associated infection/gammopathy; follow-up dermatology/infectious disease/hematology; monitor progression; distinguish from Kaposi sarcoma/xanthoma/granuloma faciale.

Common Symptoms

Red-brown/yellow papules/plaques; extensor extremities; chronic; associated infection/gammopathy

Causes and Pathogenesis

Leukocytoclastic vasculitis with fibrosis forms EED plaques.

Treatment

Dapsone; topical/intralesional steroids; retinoids; treat associated disease

Preventive Measures

Treat associated infection/gammopathy; early treatment.

Department to Visit

It is recommended to visit the Dermatology/Infectious-disease/Hematology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.