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Home > West Medicine > Other Specialties > Psychiatry
百科

Mental disorder due to Wilson disease

精神科

Common symptoms

智能障碍、不自主运动、智能减退、肝腹水、喜怒无常、吞咽困难、构音不清、被害妄想

The pathology of disease

Mental disorder due to Wilson disease (hepatolenticular degeneration) is neuropsychiatric symptoms from copper accumulation; personality change; psychosis; Kayser-Fleischer ring; chelation.

Symptoms

Personality change; psychosis; tremor; dysarthria; liver disease; Kayser-Fleischer ring; low ceruloplasmin; young

Causes

ATP7B mutation; copper accumulation; basal ganglia/liver; autosomal recessive.

Treatment

Chelation (penicillamine/trientine); zinc; low-copper diet; liver transplant; psychotropics cautiously

Dept

Hepatology / neurology / psychiatry / genetics.

Warm reminder: Health education reference only; seek care at regular hospital.