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Home > West Medicine > Other Specialties > Oncology
百科

Multiple hereditary exostoses

肿瘤外科

Common symptoms

软骨内骨化、软骨发育不良与...、肌痛

The pathology of disease

Multiple hereditary exostoses (MHE) is autosomal dominant multiple osteochondromas; limb deformity; short stature; malignant transformation risk.

Symptoms

Multiple bony masses; limb deformity; short stature; joint limitation; pathologic fracture

Causes

EXT1/EXT2 mutation; autosomal dominant.

Treatment

Excision symptomatic; osteotomy for deformity; surveillance for chondrosarcoma

Dept

Orthopedic oncology / genetics.

Warm reminder: Health education reference only; seek care at regular hospital.