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Home > West Medicine > Internal Medicine > Cardiology
I27.000

Primary Pulmonary Hypertension

心内科

Common symptoms

晕厥、疲乏、呼吸困难、咯血、心动过缓、心律失常、发绀

The pathology of disease

Primary (idiopathic) pulmonary arterial hypertension is sustained elevated pulmonary-artery pressure (mean PA >25 mmHg at rest) due to pulmonary vascular remodeling, presenting with exertional dyspnea, fatigue, syncope, and right-heart failure. Treatment: risk stratification; supportive (diuretics, oxygen, anticoagulation); PAH-specific therapy (endothelin-receptor antagonists, PDE-5 inhibitors, prostanoids, prostacyclin analogs); lung transplantation for advanced; treat underlying cause if associated.

Common Symptoms

Exertional dyspnea; fatigue/syncope; right-heart failure; elevated PA pressure; young female predominance

Causes and Pathogenesis

Pulmonary-arterial remodeling raises PVR, causing RV pressure overload and failure.

Treatment

Supportive (diuretics/oxygen/anticoag); PAH-specific therapy (ERA/PDE5i/prostanoids); transplant for advanced

Preventive Measures

Early diagnosis; PAH-specific therapy; avoid pregnancy/high altitude.

Department to Visit

It is recommended to visit the Respiratory-Cardiology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.