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Home > West Medicine > Internal Medicine > Infectious Diseases
B74.900

Filariasis

传染科

Common symptoms

乳白色尿、疲乏、发炎、表皮角化、肉芽肿、腹水、低热、反复感染、丹毒

The pathology of disease

Filariae (hematophagous arthropod-borne nematodes) in lymphatics/subcutaneous/body cavities. Acute: recurrent lymphangitis/lymphadenitis/fever. Chronic: lymphedema/elephantiasis.

Common Symptoms

Chyluria; fatigue; inflammation; epidermal keratinization; granuloma; ascites; low fever; recurrent infection; erysipelas

Causes and Pathogenesis

8 human filariae; W. bancrofti (Culex) and B. malayi (Anopheles sinensis) in China. Infective larvae/adults/microfilariae/metabolites antigenic; IgG/IgE elevated; cell-mediated also involved. Acute: hypersensitivity to molting uterine secretions/dead worms. Late: lymphatic obstruction; autoimmune factors possible. Acquired immunity neither clears worms nor prevents reinfection.

Treatment

Drug therapy, supportive therapy

Preventive Measures

(1) Mosquito control; bed nets; repellents. (2) Mass screen/treat (≥95% blood); diethylcarbamazine salt 3 g/kg salt, 16.7 g salt/person/day = 50 mg DEC for 6 months. (3) Surveillance; (4) protection.

Department to Visit

It is recommended to visit the Infectious Diseases department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.