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Home > West Medicine > Internal Medicine > Neurology
百科

Amyotrophic lateral sclerosis

神经内科

Common symptoms

手臂肌肉萎缩、驻站医、舌肌萎缩、呼吸困难、上肢周围性瘫痪、下肢中枢性瘫痪、吞咽困难、肌肉萎缩、肌肉的失用性萎缩、腱反射亢进、感觉障碍

The pathology of disease

Amyotrophic lateral sclerosis (ALS, Lou Gehrig disease) is progressive motor neuron disease; mixed upper and lower motor neuron signs; no cure; death in 3-5 years from respiratory failure.

Symptoms

Progressive muscle weakness; fasciculations; hyperreflexia; dysarthria/dysphagia; respiratory failure; no sensory loss

Causes

Unknown; SOD1 mutation in familial; cortical motor neuron degeneration.

Treatment

Riluzole; edaravone; supportive; PEG; noninvasive ventilation; multidisciplinary

Dept

Neurology.

Warm reminder: Health education reference only; seek care at regular hospital.