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Home > West Medicine > Internal Medicine > Nephrology
N28.800x004

Salt-losing nephritis

肾内科

Common symptoms

昏迷、无力、晕厥、食欲不振、氮质血症、恶心、多尿、失盐、低血压

The pathology of disease

Salt-losing nephritis is a tubular dysfunction disease of various causes, first reported by Thorn in 1944, so also called Thorn syndrome. It is a special group of renal disease characterized by severe renal salt loss, most often chronic pyelonephritis, then medullary cystic disease, polycystic kidney and nephrocalcinosis.

Common Symptoms

Coma; weakness; syncope; anorexia; azotemia; nausea; polyuria; salt loss; hypotension

Causes

Causes: chronic interstitial nephritis and chronic pyelonephritis; medullary cystic disease such as polycystic kidney; renal TB and nephrocalcinosis; bilateral renal hypoplasia; obstructive nephropathy. Mechanism: interstitial disease damages tubular epithelial cells, blunting response to aldosterone, reducing NaCl reabsorption and causing large urinary NaCl loss.

Treatment

Salt supplementation, treat cause, supportive treatment

Prevention

Treat underlying chronic renal disease and monitor electrolytes.

Recommended Department

It is recommended to visit the nephrology department; before the visit you may first book an appointment and connect with experts through this platform.

Warm reminder: The above information is provided for health education reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek care at a regular hospital in time.