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Home > West Medicine > Internal Medicine > Hematology
百科

Chronic lymphocytic leukemia

血液科

Common symptoms

出血倾向、肝脾肿大、腹泻、腹胀、盗汗、乏力、低热、肝肿大、蛋白尿

The pathology of disease

Chronic lymphocytic leukemia (CLL) is a clonal B-cell (rare T-cell) malignancy; painless, progressive accumulation of mature small lymphocytes with immune incompetence and poor antigen response. Late stage: marrow failure/organ infiltration.

Common Symptoms

Bleeding tendency; hepatosplenomegaly; diarrhea; abdominal distension; night sweats; fatigue; low fever; hepatomegaly; proteinuria

Causes

Familial (3x risk in first-degree relatives); p53 (17p13.1) mutations in 10-15%; 17p deletion 10-15%. Cytokines (TNF/TGF/IL-7/IL-5/IL-2); retroviruses/radiation.

Treatment

Drug therapy; supportive care

Prevention

Regular lifestyle; optimism; bland diet; avoid spicy.

Recommended Department

It is recommended to visit the hematology department; before the visit you may first book an appointment and connect with experts through this platform.

Warm reminder: The above information is provided for health education reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek care at a regular hospital in time.