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Home > West Medicine > Internal Medicine > Hematology

Classroom classification

百科

Chronic myeloid leukemia

血液科

Common symptoms

脾肿大、淋巴结肿大、闫铁、体重减轻、骨痛、胸骨压痛、低热、肝脏肿大

The pathology of disease

Chronic myeloid leukemia is myeloproliferative neoplasm; BCR-ABL translocation; chronic/accelerated/blast phase; imatinib/TKI; excellent chronic phase control.

Symptoms

Fatigue; splenomegaly; incidental high WBC; older; BCR-ABL; Philadelphia chromosome; chronic phase

Causes

BCR-ABL translocation; Philadelphia chromosome; CML.

Treatment

Tyrosine kinase inhibitors (imatinib/dasatinib); allogeneic transplant for blast; hematology; monitor molecular response

Dept

Hematology / oncology.

Warm reminder: Health education reference only; seek care at regular hospital.

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