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Home > West Medicine > Internal Medicine > Hematology
百科

Pediatric alpha-thalassemia

血液科

Common symptoms

脾肿大、小儿生理性贫血、胎儿水肿、腹水、溶血性黄疸、肝肿大

The pathology of disease

Alpha-thalassemia is reduced alpha-globin; silent carrier/alpha trait/Hb H disease/alpha thal major (hydrops); mild microcytic anemia; Southeast Asian; genetics; transfusion for Hb H.

Symptoms

Microcytic anemia; child; Southeast Asian; Hb H disease = moderate anemia; hydrops fetalis if Bart; family history

Causes

Alpha-globin gene deletion; Southeast Asian; Hb Bart hydrops.

Treatment

Usually no treatment for trait; transfusion for Hb H; folate; genetics counseling; prenatal diagnosis

Dept

Hematology / pediatrics / genetics.

Warm reminder: Health education reference only; seek care at regular hospital.