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Home > West Medicine > Internal Medicine > Hematology
百科

Pediatric beta-thalassemia

血液科

Common symptoms

鼻梁低、含铁血黄素沉着症、心力衰竭、食欲不振、肝纤维化、肝功能衰竭

The pathology of disease

Beta-thalassemia major (Cooley anemia) is severe transfusion-dependent microcytic anemia; children; beta-globin mutation; transfusions + chelation; bone marrow transplant; genetics.

Symptoms

Severe anemia; growth failure; frontal bossing; hepatosplenomegaly; child; Mediterranean; transfusion-dependent

Causes

Beta-globin gene mutation; beta-thalassemia major; AR; Mediterranean.

Treatment

Chronic transfusions; iron chelation (deferasirox); bone marrow transplant; genetics; splenectomy selected

Dept

Hematology / pediatrics / genetics.

Warm reminder: Health education reference only; seek care at regular hospital.