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丘疹、齿龈增生、结节、侵蚀性水疱、牙龈出血
Monocytic leukemia has specific skin lesions: purple to red-brown papules, nodules, and plaques. Acute monocytic leukemia (AMOL) may have bullous lesions. Rapid course; may regress spontaneously. Leukemic gingival hyperplasia is characteristic of AMOL (60%). Occasional gingival ulcer/necrosis/bleeding. Congenital monocytic leukemia is rare. No effective prevention; early diagnosis/treatment.
Papule; gingival hyperplasia; nodule; erosive bulla; gingival bleeding
Etiology: incidence 1-2/100,000/y; median age 65-75; M:F 1.5-3:1. Unknown; ionizing radiation/occupational/environmental carcinogens. Clonal hematopoietic-stem-cell disorder; recurrent abnormalities +8, -7/del(7q), 12p; ~40% have Ras point mutations.
Drug, supportive, radiation therapy
Avoid harmful factors; PPE; avoid indoor pollution; cautious drug use; early detection.
It is recommended to visit the Hematology department; an appointment can be booked on this platform before the visit.
Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.
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