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耳前淋巴结肿大、细菌感染、反复上呼吸道感染
Transient infantile hypogammaglobulinemia is a delayed physiologic immunoglobulin nadir in infants: transplacentally acquired maternal IgG wanes while infant IgG production starts late, causing low IgG between 3-6 months and delayed normalization up to 18-36 months. Clinical: recurrent mild infections (upper respiratory tract, otitis), no severe opportunistic infection; spontaneous recovery.
Recurrent mild upper-respiratory infection; otitis; low IgG; delayed normalization
Delayed onset of infant B-cell IgG production after maternal IgG catabolism; T/B-cell help transiently immature.
Observation; treat infections; IVIG only if severe/recurrent
Monitor immunoglobulin levels; prevent infection; spontaneous recovery by age 4.
It is recommended to visit the Pediatric Hematology department; an appointment can be booked on this platform before the visit.
Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.
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