Subacute Cutaneous Lupus Erythematosus (SCLE)

Subacute cutaneous lupus erythematosus (SCLE) is photosensitive annular/psoriasiform non-scarring erythematous plaques on sun-exposed upper body (neck/chest/back/arms), associated with Ro/SSA antibodies, mild systemic involvement (arthralgia/serositis), drug-induced (thiazides/ACE-i/CCBs/terbinafine). Treatment: strict sun protection; identify/stop culprit drug; topical corticosteroids; topical calcineurin inhibitors; oral hydroxychloroquine; systemic corticosteroids/immunosuppressants for severe; evaluate ANA/anti-Ro/C3/C4/CBC/urinalysis; follow-up dermatology/rheumatology; monitor progression to SLE (rare).

Common Symptoms

Annular/psoriasiform non-scarring plaques; sun-exposed upper body; anti-Ro; mild systemic

Causes and Pathogenesis

Anti-Ro + UV + drug triggers cause interface dermatitis (non-scarring).

Treatment

Sun protection; stop culprit drug; topical steroids; hydroxychloroquine

Preventive Measures

Sun protection; avoid culprit drugs; evaluate systemic disease.

Department to Visit

It is recommended to visit the Dermatology/Rheumatology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.