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Home > West Medicine > Internal Medicine > Rheumatology

Classroom classification

百科

Wegener granulomatosis

风湿免疫科

Common symptoms

鼻黏膜溃疡、胸痛、鼻中隔穿孔、鼻塞、葡萄膜炎、眼睑下垂、无尿、肾病综合征、角膜炎、感觉障碍

The pathology of disease

Wegener granulomatosis (granulomatosis with polyangiitis) is necrotizing granulomatous vasculitis; upper/lower respiratory and kidney; c-ANCA (PR3); rituximab/cyclophosphamide + steroids.

Symptoms

Sinusitis; otitis; cough/hemoptysis; glomerulonephritis; sinus/destruction; c-ANCA; fever/weight loss

Causes

ANCA-associated vasculitis; PR3; autoimmune; small-vessel.

Treatment

Rituximab/cyclophosphamide + high-dose steroids; maintenance; monitor kidneys/lungs; relapse common

Dept

Rheumatology / nephrology / ENT / pulmonology.

Warm reminder: Health education reference only; seek care at regular hospital.

Family room

风湿免疫科Overview of the Western Medical Room