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Home > West Medicine > Surgery > Orthopedics
百科

Polyostotic fibrous dysplasia

骨外科

Common symptoms

肌纤维大小不等、骨痛、甲状腺肿、骨皮质变薄、反应迟钝、多发性结节、低磷血症

The pathology of disease

Polyostotic fibrous dysplasia (McCune-Albright) is fibrous bone lesions; cafe-au-lait; endocrinopathy (precocious puberty); children; orthopedics/endocrinology/genetics.

Symptoms

Bone pain/fracture; cafe-au-lait; precocious puberty; child; polyostotic; endocrinopathy

Causes

GNAS activating mutation; mosaic; McCune-Albright; fibrous dysplasia.

Treatment

Bisphosphonates; orthopedics for fracture; treat endocrinopathy; pediatric endocrinology/orthopedics/genetics

Dept

Pediatric endocrinology / pediatric orthopedics / genetics.

Warm reminder: Health education reference only; seek care at regular hospital.