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Home > West Medicine > OB-GYN > Obstetrics
O26.606

Intrahepatic cholestasis of pregnancy

产科

Common symptoms

肝功能异常、疲劳、食欲不振、胆汁潴留、恶心、厌食

The pathology of disease

Intrahepatic cholestasis of pregnancy (ICP) is a specific complication of mid-late pregnancy, clinically marked by pruritus and elevated bile acids; it mainly harms the fetus, raising perinatal morbidity/mortality. Its greatest danger is unpredictable sudden fetal death, related to severity. It recurs, resolves quickly after delivery, and recurs with re-pregnancy or estrogen contraceptives. Incidence 0.8%-12.0%, with geographic/racial differences, higher in Shanghai and Sichuan.

Common Symptoms

Pruritus, elevated bile acids

Causes

Cholestasis specific to pregnancy.

Treatment

Ursodeoxycholic acid, monitor fetus

Prevention

Monitor bile acids.

Recommended Department

It is recommended to visit the obstetrics department; before the visit you may first book an appointment and connect with experts through this platform.

Warm reminder: The above information is provided for health education reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek care at a regular hospital in time.